Generic Name:Benztropine Mesylate - Injection

Brand Name: Cogentin (intravenous)

What is Benztropine Mesylate?

This medication is used as an adjunct in the therapy of all forms of Parkinsonism.  It belongs to a group called antidyskinetics, which are helpful in treating Parkinson’s disease.

This medicine is also useful in treating tremors caused as side effects when using neuroleptic drugs (for instance, phenothiazines).

How to take Benztropine Mesylate?

• This drug must be administered as directed by your doctor. Take this medication exactly the way indicated by your doctor. You may take it on a full stomach if it upsets your stomach. 

• It may take a few weeks or months before the full benefits of this medication are observed. Do not stop using this medicine without your doctor's approval. Suddenly stopping the medication can sometimes lead to a worsening of symptoms.

What are the possible side effects of Benztropine Mesylate?

Vomiting can be caused, which may be controlled by temporary discontinuation, followed by resumption at a lower dosage. Slight reduction in dosage may control nausea and still give sufficient relief of symptoms.
 
Tell your doctor if you notice any of these possible side effects: 

• Drowsiness
• Eye pain
• Skin rash 
• Dry mouth nose, or throat
• Blurred vision
• Pain or trouble in urinating
• Decreased sweating
• Constipation
• Increased sensitivity of eyes to light

Normally, these side effects are not serious. However, tell your doctor if these symptoms bother you or do not go away. Also, rarely, disorders of the nervous system such as confusion, disorientation, memory impairment, visual hallucinations may occur; exacerbation of pre-existing psychotic symptoms, nervousness, depression, listlessness, numbness of fingers may also happen.

 
 
Warnings and precautions before/ while taking Benztropine Mesylate:

• Tell your doctor your medical history, especially anything related to: glaucoma, irregular heartbeat, urination problems, allergies (especially drug allergies).

• This medicine may cause dizziness especially when rising quickly from a seated or lying position. Change positions slowly and be careful on stairs.

• Benztropine Mesylate may decrease your sweating ability making you more prone to heat stroke. Use caution during exercise and hot weather.

• Safe use in pregnancy has not been established.

• This medicine may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle.

• Alcohol can aggravate drowsiness. Limit alcohol use.

• When this drug is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, you are advised to report gastrointestinal complaints, fever or heat intolerance promptly.

What to do if you accidentally take an overdose of Benztropine Mesylate?

Symptoms of overdosage may be any of those seen in atropine poisoning or antihistamine overdosage: CNS depression, preceded or followed by stimulation; confusion; nervousness; listlessness; hallucinations (especially visual); dizziness; muscle weakness; blurred vision; palpitations; tachycardia; elevated blood pressure; nausea; vomiting; dysuria; numbness of fingers; hot, dry, flushed skin; delirium; coma; shock; convulsions; respiratory arrest; anhidrosis; hyperthermia; constipation.

Physostigmine salicylate, 1 to 2 mg, SC or IV, reportedly will reverse symptoms of anticholinergic intoxication. Contact your doctor immediately in the event of a significant overdosage.

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