Adapalene / Differin Drug Information

What Is Adapalene / Differin?

Chemically similar to Vitamin A, adapalene usually comes in gel form and is used topically to treat acne.  Scientific study suggests that adapalene affects the growth of skin cells, thus preventing acne.  In prescribed form, adapalene is spread directly on the skin and should not come into contact with the eyes, nose, or lips. 

Adapalene / differin, when used as prescribed, has been effective in the treatment and prevention of acne.  Patients who suffer from excessive side effects of this drug, however, may wish to discontinue use and consult with a physician about other possible treatments of acne.

How To Use Adapalene / Differin

 

Adapalene should be used only as prescribed by a physician.  The affected area of skin should be thoroughly washed and dried prior to use.  A thin layer is then applied to the affected area once daily, usually at bedtime. Adapalene should not be applied to wounds or burns of any kind, including sunburns.  This drug should not come into contact with anything but skin.

What Are The Possible Side Effects of Using Adapalene / Differin?

 

During the first few weeks of use, acne may actually appear worse in condition than prior to beginning of treatment.  In most people, it will usually take eight to twelve weeks for the drug to start having full effect, but by this time there should be a visual difference.  If acne does not seem much improved after twelve weeks of treatment, you may want to consult with your physician.  When properly used, the side effects of using adapalene are minimal and treated fairly easily.  The common side effects associated with this drug include:

  • Irritation

Skin may experience a stinging, or burning, sensation.  If this irritation continues, inform your physician.  

  • Redness

Blotchy or discoloured patches of skin may be observed.  Your physician should be notified if excessive redness occurs.

  • Dryness

Skin may get very dry and flaky while using adapalene.  Consult with your physician for possible treatment of this side effect.  Lotions and creams should be able to relieve most dryness, but check with your physician before use.

  • Itching

Irritation and dryness may cause an itchiness of the skin.  Again, a lotion or cream should relieve this.  If you experience severe itching, however, you should inform your physician as soon as possible.

  • Acne flares (beginning stages of treatment)

During the first few weeks of using adapalene, acne may flare up and even appear worse.  This is because adapalene causes existing acne under the skin to grow in size before effectively ending the acne cycle.

Warnings and Precautions Before Taking Adapalene / Differin

 

Adapalene has not been tested in pregnant women, so its effects on pregnant women and nursing mothers is not fully known.  Women who are pregnant or nursing should consult with a physician before taking this product.  If there is a possibility you may be nursing or pregnant, inform your physician prior to treatment. 

A common side effect of adapalene is sensitivity to sunlight.  This may cause the skin to become sunburned more easily.  Prolonged exposure to the sun should be avoided, and sunscreen used when necessary.  If you have a history of sensitivity to sunlight, inform your physician before using this drug.

What Should You Do If You Miss a Dose of Adapalene / Differin?

 

If a dose of adapalene has been skipped or missed, the patient should take the dose as soon as it is feasible to do so.  If it is close to the time for the next dose to be applied, however, it is important not to double dose.  Do not apply extra adapalene to the skin because a dose was missed the day before.  Applying too much of the drug will only increase the risk of side effects like redness, dryness, and irritation.  Only a thin layer should be applied to the skin for each dose of adapalene.

How To Store Adapalene / Differin

 

Adapalene should be stored at room temperature, away from extreme heat and cold.  Do not refrigerate or freeze adapalene, and do not expose to flame.  Adapalene should be kept out of reach of children.  If your prescription of adapalene has expired, do not continue use and inform your physician as soon as possible.

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