Movement Restored In Paralyzed Mice Through Stem Cell Therapy


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There have been a lot of wonders that modern day science has given to the mankind. At this day and age when the technology has become so advanced, people look forward that the modern day science will have an answer to all the questions that they have and it is indeed that they have gotten a whole lot answers in terms to the different questions that they had in mind. It is being thought for long that the people who are once paralyzed cannot move and that is their fate till they die because the nerves once damaged do not regenerate and that is why these individuals lose the motor and the sensory responses in their limbs, and the loss of the motor response in the limbs lead to the loss of the muscle power and tone and that leads to the paralysis of the musculature. This problem which can be caused by a severe trauma to the specific nerves supplying that limb can cause a person to be paralyzed and that is why this is considered one of the horrors in the world of medical sciences and there are a lot of people who are suffering their lives without any movement at all.

In recent years there has been a major advancement to help cure this problem so that the individuals who are suffering from the paralysis can now walk and move for the first time in their life. The scientists have taken the help of the embryonic stem cells and with the help of which they are able to form the new and functional nerve cells and connections in a mice that was paralyzed and through which they were able to restore the movement in that specific limb that was paralyzed. This is a test that was conducted on mice and that has open a new horizon in the world of people that is bleak because of the fact that they know that there is nothing that can help them and that they have to live the life as they are and this has just put them to close themselves in the dark rooms inside themselves. In this situation where there was no hope, this research has emerged as a light where these people can see that it is not far away when they will be able to move and live a normal life.

It is now being thought that as these tests have shown positive results in the individuals who have been suffering from the paralyzed condition will be able to live a normal life and this stem cell grafts will help the people who are suffering from spinal cord injuries, Parkinson’s disease, as well as other crippling diseases that affect the neurological system of an individual. The scientists said that this was something that they have been working on for about more than 30 years and this has finally given them a big breakthrough in which they can proceed their work further in hopes that in the span of some years they will be able to find a way to treat the individuals who are suffering from the neurological conditions that cripple them totally.

The scientists said that they now know as to what is the right combination of things that are needed to build the nerve cells on and they are hoping that millions of people throughout the world will find a new life with the research that they are currently doing and this will ultimately be something that the mankind has been needing for a long long time. The researcher also added that they have now got the principle on which they will build the things on and this will prove to be the key to unlock the facts that have been hidden from us for a long time.

The researchers said that there had been numerous studies that have been carried out knowing the fact that the nerves can be developed through the stem cells but the major block that the researches had been going through have been to develop the motor neurons to make functional connections to the muscles that had been stopping them from getting into the right direction where they would be able to learn as to how this process runs in its complete form and now they have made a big breakthrough in that.

The researchers said that if we are to make things simple, there are motor neurons in the spinal cord and when the movement is desired in a muscle the brain relays the message to the motor neuron in the spinal cord and then that motor neuron relays out the axons and reaches to the muscle and makes it contract through the impulses that it carries, but this process that is seemingly pretty simple in the layman terms is not that simple because it requires a lot of complex growth factors, chemicals that signal at each individual process and this movement happens at the level of the muscle. So everything needs to be put in the right order so as to maintain the right direction or else this entire research leads into the wrong direction where the results are not achieved and things finally go in waste.

The researchers said that they have find the exact combination that was required to develop the nerve cells and during the research process there were a lot of challenges that they had to face and they went through one by one and were able to accomplish the task that was there in front of them to achieve, which was defined as a first goal to achieve the bigger goal and that is where they have to go by accepting all the challenges that are going to come their way.

It all started in the laboratory when they used specific growth factors to cause the embryonic stem cells in the mouse to develop into the motor neurons. After that phase was accomplished, the researchers added the chemicals known as retinoic acid as well as sonic hedgehog protein, which helped those cells to provide an environment that was similar to the spinal cord. Then they transferred these cells into the spinal cord of the mice that was paralyzed with a viral infection. The challenge that the scientists faced was that there was a protein that was inhibiting the growth of the axons from growing and those proteins are linked to the myelin sheath that is protecting the nerve fibers, so in order to overcome the resistance, the scientists added two agents, one was the cyclic AMP and the other was the rolipram, which was a drug and then due to these two substances the axons started to grow.

Getting the axons to grow was one big breakthrough but to give these axons a destination to go from one place to another was something that was needed because they had to reach to that specific muscle to where they belong to supply the stimulus to contract. Therefore, they made a powerful neutral growth factor, which is known as GDNF near the dead sciatic nerve cells to make the connection and this worked out and with this strategy they were able to treat 11 of the 15 paralyzed mice and there were about 4100 motor neurons that were created in the spinal cord of the mouse and about 200 of the motor neurons were able to exit the cord and about 120 neurons were able to make the connection in the skeletal muscle and this is a big breakthrough that can change the lives of millions of people who are suffering from the aftermath of paralysis, because this research can just provide them with a new life.


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Job Loss Linked To Heart Attacks

Stress has always been known to cause a lot of detrimental effects on the health of the individuals and there have been a lot of problems that are reported because of the increased stress in a life of a person. Stress is known to cause ulcers in the individuals who are living a highly stressed life and along with the medications, these individuals are being asked to make their life as stress free as possible. In this article we are going to discuss regarding the stress that really damages the individual financially and also can cause heart attack and that is loss of job, which is known to affect the lives of millions of people throughout the world. This stress doubles up if the individual is to lose his job in the later years of his or her life and this can be really traumatic to that individual.

There was a study that was conducted in which there were about 4031 people who were from the ages of 51 to 61. This study was conducted over a period of time and these individuals were the ones under observation and over the span of about 10 years it was found out that there were individuals who lost their jobs and in that there were about 23 people who suffered from heart attacks and about 13 people suffered from the stroke out of the group of about 582 individuals who were laid off from their jobs. The major cause of death in these individuals was blamed upon the stress because of their need to keep the jobs and the reason to have a stable life and their dependency on that. One of the major reason for the stress because of job loss and that leading to heart attack is their fragile nature to go through that kind of an experience that is really shattering to them and thus leading them to live a much harsher life after the loss of their job, which deals with a great deal of a psychological factor that plays an important role in the part of lives of these people.

It has been mentioned that the individuals who are elderly and who are not able to work in full capacity in their jobs must be provided a place in their current jobs where they are able to work less than what they are doing now, which will help to reduce the number of individuals who go through stress and then ultimately suffer from heart attacks. It is also of great importance that there must be centers that are developed that would work to counsel the individuals who are elderly and help them go through this process very smoothly because at an elderly age there are a lot of health related problems and other factors that does not allow them to work in full capacity and if there are such centers, there would be better outcome in terms of helping them find the jobs that they can do in their capacity and also counseling them so that they can understand that what is the thing that is in their best interest.

One of the biggest fears that are being faced is the loss of health coverage that these individuals have through their employment because they are relying heavily on their health insurances and when these are being taken away, this just adds the burden on their thoughts as to how they are going to cope with that and how they would be able to manage their life with such and these things just put a great toll on them and hurts them really bad and results in the worst outcomes that can be faced by these individuals, death.
The researchers who were conducting the research on the aged people said that it was not surprising to them that loss of job could have such an effect on the elderly people because these days the life is becoming too difficult to live and that things are getting pretty expensive, especially the health and that the elderly just cannot help themselves in getting out of the depression and anxiety that they are going through, which then ultimately works to take them out of the misery of life by taking their life.

The learning that we gather from the effects the job loss in the elderly bears is that we should understand and learn as to what are the different things that they are going through, what are their problems that need to be addressed, how we can support them as a human because these are the individuals who still want to work and earn, but that opportunity is being taken from them, what are the reasons that put them through so much stress, is that the worry of health insurance? Do they worry a lot of their extinguishing finances that are going to burn out the moment they are going to lose their job because they are living pay check to pay check. There must be a lot of problems that I am sure they must be suffering from and that is something that we need to understand and see as to what are these places where we can help them live and sustain their lives better. I think we can do it and this just needs our attention, dedication and devotion and sincerity to the cause.


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IVF Giving Hope To Late Mothers

Infertility is gaining its ground pretty fast and now one out of every six couples are suffering from the problems of infertility where about forty percent of the problems of infertility are linked to the females and about forty percent to the males, whereas twenty percent of the problems are linked to both the males and the females. The couples who are going through the problems of infertility are suffering a lot psychologically and is a lot damaging to the mental health of the couple. The problem of infertility has long been a problem, but this problem has been overcome by the efforts of two doctors who have given a great hope to a lot of couples throughout the world and now the couples who are going the problems with infertility can have their child with the procedure of in vitro fertilization. The two doctors who have introduced this procedure are Dr. Edwards and Dr. Steptoe who have provided a lot of couples with hope and this procedure was being introduced in the year 1978 for the very first time.

Now this procedure is being used through the entire world where the couples have been going through the problems with infertility and this technology has since been refined by a lot of physicians and embryologists throughout the world and there have been 20,000 babies that have been born with this procedure. The chances or the possibilities of a continuing pregnancy being achieved have been enhanced from about none to one chance in four to six at the centers where the in vitro fertilization is being performed.

There are a lot of variables on which achieving a pregnancy in a couple is achieved and it varies from couple to couple and these variables include age, the reproductive health of both the man and the woman who want to achieve pregnancy and the chances of the in vitro fertilization also varies from case to case for that reason a complete evaluation is being required so that the chances of pregnancy can be determined in the given situation.

In the process of in vitro fertilization the egg is being obtained from the ovary by a needle that is being placed under ultrasound guidance and this ultrasound guided procedure has taken over the surgical procurement of the egg. The best thing that the ultrasound guided procedure offers is that the woman who is undergoing that procedure does not need to undergo hospitalization neither general anesthesia because both these have their own risks and complications profile.

Before obtaining the egg through the transvaginal ultrasound guided procedure, there is a proper environment that needs to be prepared in a woman so that the chances of getting the multiple healthy and mature eggs is possible and for that reason the woman just goes for about two weeks of extensive preparation. In this procedure, the woman goes on the fertility drugs and then the blood tests are being done and then the ultrasound scans are being performed of the ovaries so that the optimal time to retrieve the eggs from the ovary is being defined and the optimal time to obtain the eggs is the ovulation time because it is when the eggs are ready to be fertilized.

Around the time of ovulation the patient is prepped and draped and under sterile conditions and under the transvaginal ultrasound guidance a 16-gauge single lumen needle is passed transvaginally and then the eggs are being obtained. The women who have gone through this procedure has said that there is mild discomfort that is being felt and that is very much similar to the pap smear or the endometrial biopsy that is being taken. Once the procedure is being done, then the patient can go home in a short time and they can do their activities of daily living.

After that the fluid that is being obtained from the follicles is being examined under the microscope and then the eggs are being located and then the sperms are being placed within the eggs. The eggs then start to cleave down to indicate that the process has started and then after two or three divisions that the egg goes into, it is then known as the preimplantation embryo. These embryos are then kept in the laboratory and then in a mixture that acts as a substitute for the environment that would have been provided by the fallopian tubes. After that the embryos are then placed in the uterus by passing it through the vagina by using a special catheter and then when the embryo has been placed in the uterus, the woman is asked to lie in the bed quietly for about an hour or so and then she is asked to return home.

After that the embryo starts to develop inside the uterus and then the woman goes through the regular checkups so that the fetus in the mother’s womb can be checked regarding growth. It was important that the entire procedure of the in vitro fertilization is being explained in detail so that you must know as to what are the different things that are involved in that. Now this procedure is a great hope for women who want to be pregnant in the late ages and along with this process there is also a breakthrough in getting the embryos frozen for women who want to preserve the embryos and a new technique has been developed where the problems with the thawing of the embryos has been eradicated and that has brought a big hope for the women.

There are also women who are going through the cancer treatments and also the other life threatening conditions in which they have to go through the aggressive therapies and have a chance to get their ovaries affected by these treatments, then they think that their eggs be preserved so that they are able to conceive once they are in a stable condition and their cancer is in remission, which is a big hope for these women. The process known as Cryotop in which the embryos can be frozen more rapidly, which can remove the ice from them and prevent damage to the embryo and through this they have come to manage about 90 percent survival rate of the embryo and a high pregnancy rate of about 42 percent which is the same as can be achieved through a fresh egg. This process has helped eliminate the infertility problems in which the eggs are produced for a specific time span.


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Signs Of Early Dementia

Our body is a major indicator if any of the problems are arising in our body and the major indicator for the neurological disease are exhibited with problems of walking, balance and coordination, which can signal an early sign of dementia, as well as Alzheimer’s disease.

The findings that were shown were present in about 2000 people which included the ages of 65 and older and these individuals had been followed for about 6 years and before that time none of them had shown any sign of Alzheimer’s or dementia.

There was a link that was found between the mind and body of the patients who were aging and there was also a link that was established between the walking and the later problems with dementia.

The link mentions that as an individual gets aged, their walking slows down and as the walking slows down the odds increase that their mind processing is also getting slow, which often leads to Alzheimer’s disease and that is something that can be found with the change in gait and the mind processing, which act as an indicator.

The researcher said that earlier there was a concept that the earliest changes that occur are presented first in the form of cognitive changes or the problems with the mental processing. It was also said that the physical problems appear earlier than the disease itself. He said that the individuals who were having a lot of difficulty in terms of walking were the ones who were to have a higher rate of developing Alzheimer’s disease in the next six years.

These people who were being tested throughout the duration of observation were put through different tests such as walking, balancing, cognitive skills etc. were found to be the ones who were at less risk than the ones who were showing problems with walking, thinking and balancing. These individuals were retested after every 2 years.

They also mentioned that the things are all linked and if one thing goes wrong, the other things starts to go wrong along with it. The researcher also mentioned that one does not want the people to read that if they are having difficulty with walking means that they will have problems with their mind and they will go onto develop dementia or Alzheimer’s because it does not happen like that all the time, the physical signs may be an indicator but not for sure.


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Breast Cancer Is Fought By A Bone Loss Drug

According to a new research, a bone loss drug, which is Raloxifene, which reduces the resorption of the bones can reduce the chances of women suffering from breast cancer. The researchers who have been studying the effects of the drug, Raloxifene, said that this drug works equally good as the drug tamoxifen, which is being used as an agent to kill the cancerous cells that are caused by the breast cancer.

We would like to give you a brief introduction of breast cancer so that you can gather an understanding of this leading cause of death in women; breast cancer is the most prevalent and common cancer among the women and the number of cases reported of breast cancer are increasing a lot. As an estimate there are about one million women who are currently suffering from breast cancer.

There are many factors that lead to the development of breast cancer and one of them is age. It is being estimated that the incidence of breast cancer in women increases after every 10 years and it just increases with every decade until the women they hit their menopause and it is then that the risk of developing breast cancer starts to decrease. From the research and analyzing the different data that was gathered from throughout the world, it has come to known that out of every 100,000 women about 24 women in Japan will develop cancer where as in China this rate climbs further to about 26. These numbers increase pretty high in Britain where it is about 68.8 and in Scotland it is 72 and in US it climbs up to about 90.7 per 100,000 females.

It has also been established a fact that if the women from any of these countries travel to US or from any of the low numbered countries, then it is being seen that the breast cancer cases will come to the same level of that country in a matter of a few decades, which shows that apart from the genetic influence in getting the breast cancer, it is also the geographical variation that has a strong influence on developing the breast cancer.

Another factor that can be the cause of breast cancer is the reproductive factors, the women who are either menstruating early or are going through a late menopause are likely to develop breast cancer. Also the women who give birth to a child at late ages are at risk of developing breast cancer and the risk is doubled in these women than the women who are giving birth to a child in their 20s. It is also being stated that the women who give birth to their first child at the age of 35 are the ones who are at the most risk than the women who have no children at all.

Another cause of breast cancer among women is the inheritance of the genetic makeup, which accounts for about 10% of the women all around the world. Another factor that is the cause of the breast cancer is the presence of a previous breast disease that can account for the development of breast cancer.

Another factor of breast cancer is the radiation exposure. It has been mentioned that the teenage girls were the ones who developed the breast cancer due to the radiation exposure during the World War II. The women who are obese before reaching to their menopausal age are less likely to develop breast cancer where as in the postmenopausal women the increase in weight doubles the risk of breast cancer in them.

These days women are being going through constant breast examinations and breast screenings and the women are also asked to self breast examinations so that they are able to check whether they are developing any lumps that must be given serious attention to.

If the cancer is being found then the women are being told about the different tests that they would be going through and what are the different options that they have in terms of treatment of the breast cancer and what are the risks and benefits of the different treatment options that will be instituted as the best approach that is present at the current time. Therefore it is best that if you find a lump in the breast, that you must consult a physician and get that checked immediately. There are a lot of breakthroughs that are going on in the current world of medicine where there are a lot of drugs that are becoming available to the women that are much safer and more specific for the treatment of breast cancer and thus is a great hope for the women who are suffering from it.

According to the recent research, the scientists have been able to find out that there is a drug that is equally effective as the drug tamoxifen and that it reduces the incidence of breast cancer by 50%. Raloxifene is an osteoporosis drug and is being given to women to help protect their bones.

There was a study that was conducted in which the data was collected of about 20,000 women who have reached the phase of menopause. It was found that the raloxifene was comparatively a safer drug than the tamoxifen because it caused less uterine cancers and very few blood clots that were life threatening. The researchers also found out that if we see the effects of the drugs and the quality of life issues, there were a lot of women who said that they had side effects from both of these medicines, which are raloxifene and the tamoxifen, but the raloxifene did not have much of a negative impact on their quality of life.

The symptoms that these women had with the tamoxifen were having were leg cramps, problems of bladder and gynecological problems. Whereas the women who were on raloxifene had been having aches, pains during intercourse and weight gain. It was also mentioned that the drug raloxifene is going to be a drug of choice for women who are at risk of developing breast cancer and that they will have an alternative now, which is going to be the most excellent aspect of it. The researchers said that raloxifene is still in the process of being approved by the FDA and they are hoping that it will get approved and will be a big hope for millions of women throughout the world.


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Beware Of ADHD Drugs

According to a report there were thousands of children and adults who were being sent to the emergency rooms because of using the ADHD drugs.

There was a survey conducted in which it was found that there were about 3100 people that were being sent to emergency room each year because of the usage of ADHD drugs and most of the cases that are reported are because of the overdose and accidental use of the drug, which the researchers say can be prevented by placing the pills out of the reach of children.
There were other patients who had side effects from the ADHD drugs and the side effects include chest pains, stroke, increased blood pressure and increased heart rates.

Since these cases were being reported at a higher rate, this caused the doctors concerned and they have asked the FDA to issue a warning on the usage of those drugs and the drugs that are given in ADHD includes Ritalin, Concerta, as well as Adderall.

There are some doctors who say that the sides effects are small and they do not think that the drug offers any harm to the individuals and that the most cases can be prevented by taking the drugs out of the reach of the children. There are about 3.3 million Americans who are the ages of 19 or younger and about 1.5 million of people who are the ages of 20 or older who are taking the ADHD medicines.

There were about 19 deaths that were reported from about 1999 till 2003 and there were about 54 cases that were reported of heart attacks and strokes, there were also other patients who had prior heart problems. There were about 188 emergency room visits that were reported from about August 2003 till December 2005 because of the side effects of these drugs and this data was collected by different hospitals.

There were some other cases reported that were linked to the allergic reactions with the usage of the ADHD drugs, which was reported in about 73 patients. There were also cases reported in which the child used the medicine of some other child or used his medicine but in an excessive dose.

The symptoms other than the cardiac symptoms included pain in the abdomen, spasms, rashes, weakness and pain in the limbs, but there has been no report of the patients being dead with the use of the drugs of ADHD.

There is still a debate going on among the different doctors as to whether they should label this drug as a black box or they should wait and see more data that they come up with.


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You Can Pull Yourself Out From Strokes Effects

Stroke is a condition in which the blood supply to the brain is altered or stopped, which results in the damage to the brain cells. The damage to the brain cells is irreversible and can lead to temporary or permanent loss of functions. The individuals who suffer from stroke are generally asked to go through a rehabilitation process where they are made to go through the different exercise regimens, which are totally focused to help these individuals to gain strength and to make them able to perform the skills that they have lost because of stroke.

The most important thing that makes the foundation of the physical therapies is an elaborative discussion with the individuals who are going through it. It is very important that they should be told as to what happened and what were the different skills that they lost due to the stroke and what can be done to help regain it back. These kind of discussions just help the individuals to understand as to how much effort will be required and that they need to keep themselves strong through the entire process, as their will is the most important thing that would just make this all possible.

The main purpose of the rehabilitation of stroke patients is to assess the extent of damage being present and then the duration of the rehabilitation is assigned and then the individuals go through an extensive exercise regimen. For example the individuals who has a severe affect on their lower extremities due to which they cannot walk will have to go through a rehabilitation period of about 11 weeks and if the individuals have not regained their strength and the functionality of that limb to a 100% then the duration of the therapy is increased and is made more intense.

The doctors state that even though there are neurological impairments because of the stroke, but the brain has the learning capacity and the individuals can learn to do the basic tasks of their living.

In a study on patients that have suffered from stroke included men and women and they were suffering from problems with walking. There were two blocks of the patients made, one block was made to exercise on the treadmill and the intensity and the duration of the exercise varied among different individuals depending on their level to cope up with that. The other block of patients were made to do the conventional therapies and these were for about 40 minutes with stretching of about 35 minutes and treadmill exercise of about 5 minutes.

After a span of about six months, it was found that the individuals who were going through an intensive program of the treadmill exercise were the ones who had about a 56% improvement in walking ability as compared to the individuals in the other block who were in the traditional group who had an improvement of only about 12%.

Even if you are an individual who had gone through stroke and you had a resultant weakness of your legs and because of that you are unable to walk, then you must know that you can just get yourself back on track no matter how long it has been since you had stroke, you can walk, you can, and you know that.


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Genetic Disorders Detected By DNA Fingerprinting In Embryo

Genetics is the future of the modern day science. There are a lot of diseases that have a genetic influence behind them and it is how they are caused. The researchers now are trying to find the ways as to how they can be able to detect the different genes that are the cause of the diseases so that they are able to detect these problems in the embryo and eliminate them before the child comes into the world. Isn’t that amazing that a child who is going to born with a problem of autism, now have the opportunity to live a life where he is going to be a normal child and will not suffer from the disastrous effects of autism. We are talking about future where millions of people who could have suffered from serious illnesses now have a chance to live a longer, happier and a bright life, I think that is awesome and that will lead to a healthy world with long term life expectancy.

In this article we are going to discuss the different diseases that are being detected through the genetic testing and their genes are being marked and that is going to be just the beginning of this new era.

The geneticists have now been able to get really close in finding the genetic basis of the metabolic basis, which includes hypertension, obesity as well as diabetes. In this study the researchers studied about 1300 patients, as well as volunteers who were healthy and in them the researchers were able to find a great deal of variation in the sequence of the DNA, which was lipid phosphate SHIP2 gene, which is linked with the heightened risk of developing the metabolic disorder, which is also known as the syndrome X. The researchers are still working on it to get to the culprit genes that are the cause of the metabolic syndrome, which includes hypertension, diabetes and dyslipidemia that can ultimately result in the vascular problems as well as the cardiovascular disease.

Another gene, which is known as SHIP2, which controls the biological aspects of the insulin, which is a hormone produced by pancreas. This regulates the biological effects of insulin that functions to lower the sugar level in the blood. In syndrome X, there is decrease in the action of the insulin to lower the blood sugar level that results in the development of diabetes. The researchers added that they need to do more studies so that they are able to gather more data and get to the genes that are causing all these things to happen in individuals and that is going to be a major breakthrough once it is being sorted out because these genetic disorders can be cleared out in the embryos.

So the scientists are now coming up with the tests that would enable them to find these genetic disorders in the embryos and then this would help the couples to prevent passing on the bad genes to their kids.

The scientists said that there are a lot of diseases that pass on through the genetic route and with the different techniques that are being devised these days they would be able to save millions of people from falling a victim of those diseases and there can be millions and millions of dollars that can be saved and the world can be a much better place with greater life expectancies.
The scientists mentioned that testing the parents, as well as the kids and close relationships can help the scientists to identify the markers, which are the different genes that are the cause of the diseases. There is a new test that is being introduced, which is known as pre-implantation genetic halotyping, also known as PGH, which will be providing lots of couples to help prevent passing of the serious illnesses to their children so that this can be made sure that the embryos that are used in the in-vitro fertilization are healthy.
The researchers added that with these genetic testings, the embryos are screened for the known genes of various diseases and this is being done with taking one single cell from the embryo and then amplifying it to a million times in the laboratory and it is from this that these scientists are able to know as to what are the different culprit genes that are there and should be eliminated from the embryo so that the embryo is free from these genes and the child who then comes into the world is almost totally free of disease.
When the scientists have taken out the cell from the embryo and checked under high amplifications then there is a very little chance that the results could be faulty. The parents and close family members are also tested so as to determine as to what are the different chromosomes that have the culprit genes in them. And then these faulty patterns that are obtained from the parents and the close relatives are then compared with the patterns obtained from the embryo and this shows whether the culprit genes were in the embryo or not.

With the pre-implantation genetic halotyping it is also possible to know that whether the embryo is just only a carrier or it has the genetic condition in it that would ultimately lead to diseases. If there is no such condition in the embryo then the embryo is known as healthy.

This test has helped about five kids who might have contracted the Duchenne muscular dystrophy and that risk has been eliminated from the embryos who will grow out to be healthy individuals, which is a huge success that this modern day technological advancements have given to us.


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Stress Causing Infertility In Women

Stress is a very big factor that is prevailing throughout the world. There are a lot of people who are suffering from stress and it is affecting their life in an adverse way. It is really shocking that the stress in the world is increasing as the time is going on and does not seem to be lowering in any way. In this article we are going to discuss the effects of stress in causing infertility in women and this has been a great concern among the women because stress is becoming an accelerated cause of infertility in women. It has been reported earlier in different journals that stress is causing a lot of problems to the individuals and the reported evidence is that stress can cause ulcers and it also imbalances the chemistry of the body and thus results in a great deal of problems inside the body.

Another breakthrough that the scientists have been able to find out is that the women who are suffering from high levels of stress, this causes high level of stress hormone in the body that results in stoppage of the ovulation and thus the women are unable to conceive. There have been about forty percent of women who are linked to the cause of infertility and also about forty percent of men are linked to the causes of infertility and in about twenty percent of the cases there are both the men and women who are the cause of infertility.

The other causes of infertility in women apart from stress includes hormonal disorders, blockage or damage of the fallopian tubes, endometriosis is also a cause of infertility because there is presence of the uterine lining elsewhere other than the uterus. The causes of infertility in males include the low sperm count, de-shaping of the sperm and decreased motility of the sperm.

In this article we will discuss about the stress being the major cause of infertility in women and the major reason for this is a lot of responsibilities being on their shoulder where they have to be up from very early in the morning till the kids go to sleep as well as abusive attitudes that they have to bear and severe marital issues through they have to go. It has been analyzed that the women who are at risk of being infertile because of stress are mostly in a denial phase that they are not stressed and it has been found that the women who are going through severe stress in their lives can be helped with the talking therapies, which can reverse the harmful effects of stress in their lives and can improve the chances of the women getting pregnant.

There was a study that was conducted on about 16 women who were in their 20s and 30s, these women were of a normal weight but they did not have a menstrual cycle in a period of about six months. There were blood samples taken of these women to find out the picture of the blood and it was found that these women who have not had a period in six months and when the blood levels came back, there was a spike in the levels of the cortisol, which is also known as the stress hormone.

After getting the blood tests showed that there was a high level of cortisol in the blood, these women were given the cognitive behavioral therapy, as well as rest. The researcher added that the women when asked if they were going through any stresses they denied to it and said that everything is going fine in their life. The researchers added that the individuals who mostly report that everything is going fine in their lives are the ones who are mostly suffering from severe stress.

The researchers added that these women who say that they do not have any stress at all are actually possessing a nonrealistic attitude and they just do not realize that they crack with the severe stress but they do not understand stress in its true terms. The researchers stressed upon the fact that the lifestyle of different women have a direct effect on their life and that has a lot of influence on their menstrual cycle.

The women who had been given the cognitive therapy, as well as rest, there were about 80 percent of the women how had started to ovulate again as when compared to the women that were in another group and then after a span of two months there were about two women who got pregnant.

The research coordinator added that their study solely included women whose menstrual cycles were stopped, but it was also said that their study implies to the women who are still menstruating but have fertility problems, this study implies to them as well. Another very important point that was added was that it was possible that there are a lot of women who just only can benefit from the reduction in stress in order to treat the problems with infertility.

The researchers added that they are going to do a much bigger study than this so that they are able to have a bigger picture to see the results from that study and compare to the results of this study and if the results are going to match then this would just be a very strong evidence that the stress has a very big role in causing infertility in women and that this could become a part of detailed history taking that is being taken to determine the causes of infertility.

Another very important fact that was added was that the women who are suffering from infertility, there are about 20% of women who are suffering from the problems with ovulation and there are a lot of women who have problem with increased weight. It is known since long that the lifestyle greatly affects the menstrual cycle in women and that it can become a part and parcel to determine that whether the stress is cause of infertility and that cognitive behavioral therapies be instituted to treat the women who are suffering from infertility as an approach to treat it.

Therefore with decreased stress levels there can be much better chances at getting conceived and thus the research pointing out to stress as a reason of infertility can greatly help a lot of couples achieve pregnancy.


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Detection Of Bladder Cancer In An Easy Way

Earlier the test that was used to diagnose bladder cancer was cystoscopy, which is an invasive procedure, but now there is introduction of a new test, which is known as the urine test through which the bladder can cancer can be diagnosed.

The urine test that is going to change the world of diagnosing the bladder cancer as this is a noninvasive test and will prove to help a lot of people throughout the globe. In this test, an enzyme telomerase is being measured, which is a major part of cellular repair. If the levels of this enzyme are abnormally high, then this represents the presence of a bladder cancer.

The most important thing that the urine test is going to help with is that it will cause an early diagnosis of the bladder cancer and will help millions and millions of men throughout the world.

According to the statistics, there are about 64,000 people all around the world who suffer from the bladder cancer each year. The bladder cancer is more common in men than in women. According to another statistic there are about 13,000 men who die each year from bladder cancer.

The first indications of the bladder cancer is that there is an increase in the frequency of the bathroom. Currently in order to diagnose the bladder cancer, the individuals go through a very painful procedure of cystoscopy in which a tube is inserted through the urethra and then it is moved into the bladder. There is a camera in the tube that helps the doctors visualize the internal lining of the bladder and they can remove the tissue of the bladder so that they can perform the histology analysis on that tissue and then make a diagnosis of the bladder cancer.

Even though the cystoscopy gives an accurate diagnosis, this procedure is very painful and bears risk of infection and bleeding. On the other hand the urine test is not invasive and it is easy to perform and gives an accurate diagnosis of the bladder cancer by detecting the abnormally high levels of telomerase.

According to the recent statistics, the smokers have a very high incidence of developing the bladder cancer and this discovery is going to help a lot of men throughout the world.


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