Warning: count(): Parameter must be an array or an object that implements Countable in /home/healthca/public_html/blog/wp-content/plugins/UltimateTagWarrior/ultimate-tag-warrior-core.php on line 1390

There are millions of people throughout the world who have been suffering from chronic pain due to a lot of reasons. A lot of people are just suffering from the pain every single day and they are not finding any relief from the pain that they are going through. Pain is a very big factor in their life due to which they are unable to have a quality of life. These people take a lot of narcotic drugs to relieve their pain and even get injections into their joints but they are unable to manage the pain even after taking so many medications. There are a lot of people who are just so afraid of developing addiction of these narcotic drugs. When it is being asked from the people as to how often they suffer from pain, they just say that they have been suffering through it most of their lives and it has just been like that for them for a very long time and that they just do not know as to what they are going to do in their life.

One of the individual who was going through pain said that his life has just been a living hell and that he can do anything if he is free from pain because he just wanted to get rid of it no matter what. It is like him that a lot of people are suffering from pain and that they just get injections and pills for that but it just does not seem to go away. Since people do not get any benefit from the different therapies that are offered by medicines, they just divert on to the other treatments offered by the different alternative therapies. Lot of people just want to try the herbal remedies so that they are able to find a way out of their misery. There is a new research that is being conducted in which it has shown that there is a new cooling off treatment that can give relief to the millions of people throughout the world that are suffering from arthritis or pain due to nerve damage.

There were recent studies conducted in which the researchers tried to help the pain by cooling off the skin, these individuals were having sprains, joint pains and inflammation and they found that the individuals who were suffering from pain found a pretty good relief with that therapy. It is also interesting to note that the Chinese use the same remedy but in a different way, they use the mint oil that works the same way as cooling off of the skin in the modern way. It has been found that the chemicals that are being used to treat the pain are almost the same kind of chemicals that are present in the mint oil. The active ingredients in the mint oil can kill the pain just as the cooling effect of the skin is going to do with the different chemicals that are being found in the research.

It has been found that the active ingredients that are being used to produce the cooling effect on the skin possess minimal side effects but they are proven to relieve the pain of the sufferers who had been suffering from the pain for long and these individuals were the one who found no pain relief with the pain medications. In the recent studies, the researchers have found the active ingredients in the mint oil, as well as the chemicals used for the cooling off process act on a receptor that has been newly found and that these chemicals bind with this receptor and exert their effects.

The mechanism with which the things work with these cooling off chemicals is that there is a known receptor known as TRPM8, which is activated by these chemicals and with the cooling off effect, which is caused by the lowering down of the temperatures, there is inhibition of the pain messages from the place of the pain to the brain and thus this inhibition of the signals causes the individual to not feel pain at all. The researchers believe that the medicine that they will be working on will be just applied to the skin in very small doses and then this will take away the pain from which the individual is suffering. This is going to be wonderful if the people are going to find the relief of pain by just applying the cooling off chemical to the skin and are able to relieve their pain. This way there would be a lot of people who would not have to rely on the pain medications that they had been taking for so long and they would be able to prevent themselves from the dependent effect of these medications.

It is important to note here that the conventional strong medications such as morphine are the effective medications to relieve the chronic pain but when they are taken for long periods of time they just turn out to be ineffective and thus they are just unable to control the pain. The researchers believe and hope that this new therapy to relieve pain is going to be the mainstay of the new frontier to control pain.

Tags:  

Kidney is one of the major organs of our body. The function of the kidney is to clear the toxic substances from the blood and hence making the blood purified. This purified blood then circulates through the body and returns again to the kidneys where it is being filtered again. It is really important for the kidneys to function properly but when there is any damage or structural deformity or blockage of the renal arteries or veins, then this leads to a host of symptoms. It is really important that if there are symptoms concerning the kidney functions such as pain in the lower flanks, hematuria, dysuria, etc. the individual must report to a doctor to ascertain as to what is the cause of these symptoms. It just greatly helps to manage the situation when diagnosed at an early stage. In this article we are going to discuss the new technique that is being found to treat the blocked arteries that can really prevent the kidneys from dying.

When an artery in the kidney is blocked, the conventional approach to deal with it is to remove the agent that is causing a block in the arteries, angioplasty, as well as stenting. In the recent study it was suggested that with the approach of minimally invasive angioplasty, as well as stenting that is done to restore the blood flow, there can be a suction device placed in the artery to remove the material that is blocking the artery. Of note, the kidney surgery is one of the major operations that the individual has to undergo and it has its complications, but with the minimally invasive approach it was found that after three to six weeks of it, the kidney was almost about or equal to functioning as a normal kidney as would have been achieved with a major surgery, which was an awesome result. The doctors who performed this surgery said that they are very hopeful that this type of kidney surgery is going to bring hopes to a lot of individuals who are going through the kidney damage and this new way of doing angioplasty and stenting would open new avenues of much better results.

The success of this new approach lies in the usage of the suction whose main function is to prevent buildup of the plaque or other materials that are the cause of the blockage of the arteries of the kidneys and ultimately cause severe damage to it. It was also said that with the approach of angioplasty without the use of the suction device that filters out the artery, the results have been very inconsistent.

Just to lay out a brief understanding as to what angioplasty is, it is a procedure in which there is a device like a balloon that is being inserted into the artery and then inflated, which results in the crushing of the fatty deposits inside the arteries that are causing their blockage. With other approaches, there is also a stent that is being inserted into the artery whose function is to keep the artery open or patent so that it just does not collapse back or build any plaques inside. Whereas in this approach the balloon is inflated into the vessel and then the suction system works to pull out all the debris that is causing the blockage out of the artery so that there are no remnants that can further cause the artery to block. In the study there were about 32 patients who took part and were in their late 60s. With this approach it was found that the kidney function was improved in about 50 percent of the patients who underwent through this procedure and the astonishing fact is that there was no individual in whom this procedure had caused any deterioration. The arteries that were narrowed were reopened in all the patients who had undergone this process and the blood pressure of these patients fall from 178 systolic to 158 systolic, whereas the diastolic pressures decreased from 81 to 76.

The experts said that the impairment of the blood flow is common in the individuals who are in their late 60s or 70s and thus this makes these procedures very common. It has also been found through the research data that there are about seven percent of the healthy older Americans who are suffering from narrowing of the renal artery or the narrowing of the main artery going into the kidneys. It was estimated that there would be about 40,000 Americans who would be requiring surgery to treat this condition.

The major complication of the narrowed blood vessels of the kidneys is that it causes high blood pressure and thus it makes the situation a whole lot worse because this can lead to heart attack, stroke or death and therefore it is really important to treat this condition as soon as possible and makes this situation an emergency.
Thus this new approach holds promises that the narrowing or blockage of the arteries is a condition that will be dealt with in a more secure way and to make sure that there will be more secure ways that will surface as the time goes on.

Tags:  

Allergies are a growing concern throughout the world, especially in children. There was a recent report in which it was mentioned that the asthma and allergies is a rapidly growing phenomenon in the young. In the year 1991, there were studies conducted on the global prevalence of asthma, hay fever, as well as eczema. Another study was conducted in about 2002 and 2003 where there was the repeat of the surveys to see if there are any changes and in that study there were about 193,000 children who were in the ages of 6 to 7 years from around 37 countries. In the questionnaires these children were asked about the presence of the symptoms of asthma and allergies, which was wheezing and another set of children who were of the age of 13 to 14 years from different countries were asked the same questions and it was found by the researchers that there is a high trend of allergies among these children and there were a great incidence of cases reported for eczema as well as hay fever.

This regional study showed that there was a decrease in the symptoms of asthma that was known to be of high prevalence previously, but there were still countries that were showing these problems to be on the high side, which included the countries in Asia-Pacific, as well as India in both of the age groups mentioned above. There was also mentioned by the researchers that there is a lot of work that needs to be done in terms of awareness and the environment as well as the treatments available for the allergic symptoms because a lot of the children are suffering from these problems because there is no proper management to make them aware as to how they can protect themselves from the allergic problems as well as making them aware of how to cope with the different allergic situations so that these children can live a better life.

The experts think that there are a lot of things that still need to be explored as to the new treatments of the allergies, as well as the exact causes that result in the allergic conditions in children. There are a lot of cases of allergies in children that are reported in the different seasons. It is known that these allergic conditions can cause serious health issues and that can even lead to death if these are not dealt with in an appropriate fashion. There is a general question that arises as to why there are growing cases of allergies that are happening all over the world. The major reasons that are yet known are the different environmental conditions, pollution of the water, as well as food, hygiene, as these cause a drop in the immune system and that results in the causation of other diseases that found a good ground to infect these children in the absence of the body’s own defense system.

Experts say that with prevention there are a lot of cases of allergies that can be prevented. For example if the individual is suffering from allergies, they can protect themselves from the allergens that are in the environment such as pollen, so for them it would be good if they wear a mask when they go out, which would protect them from inhaling the pollens that are acting as an allergen. There are individuals who suffer from allergies that are due to the pets such as cats, so it is better that they avoid coming in contact with the cats so that they do not suffer from an allergic reaction. The hygiene of the house is another important factor because the old carpets have a lot of dust in them and that just results in the dust particles in the home environment on a constant basis and that just aggravates the allergic symptoms. Molds, mildew are also a big causative factor that result in the development of asthma and other allergic conditions and these can be averted only by making sure that the environment is free from all these so that a better quality of life can be maintained.

There was another study conducted in which the focus of the study was to find the prevalence of the allergen exposure in about 1,300 children, and in this group there were about 500 children who were known to have risk factors for allergen sensitivity at birth. It was found that in about 90 percent of the cases in which the children were experiencing the symptoms of wheezing but they were not at risk for any allergies were the ones who lost the symptoms at school age and they had the normal lung functions at the ages of 13 and 14. On the other hand the children who were found to have repeated attacks of wheezing and sensitivity to allergens in the beginning three years of their life are the ones who are prone to develop the symptoms of loss of lung function as well as asthma.

The researchers also added that the term asthma should be totally removed as a term because it is a cluster of different things that include wheezing, cough, sputum production, difficulty breathing, and is caused by the inflammation of the air passages. The experts and researchers who are working on finding as to how these different allergens work their way to cause the allergies are still to be explored and the effective treatments that can totally alleviate the symptoms and help the children to develop such allergies in the later years of their life.

Tags:  

There is a recent concern that is being brought up by the use of one of the attention deficit hyperactivity disorder known as Dexerdrine. This drug is known to provide benefits to the individuals who are suffering from the ADHD but according to the recent reports this drug can cause serious side effects in individuals who are suffering from heart disease. Since this drug is a stimulant, so it can cause unwanted side effects.

There was a notification in which the Food and Drug Administration has asked the pharmaceutical companies who are making the drugs to treat the ADHD should add a warning label on the drug Dexedrine for the patients who are suffering from heart disease. This warning was issued because there were some instances where the children and teens who were suffering from heart diseases who have taken this drug resulted in sudden death. The other side effects of this medication included hallucinations as well as delusional thinking.

One thing that was still unclear was that it is not known whether it is only Dexedrine that should not be taken or the other ADHD drugs must also have that label on them so that the individuals who are suffering from heart diseases must not take that drug as well. It came to knowledge that the Food and Drug Administration has issued the warnings on the newer ADHD drugs, but since Dexedrine belonged to an older class there has not been any warning issued for that specific drug, but now FDA has ordered to add a warning label for that drug.

There had been some conflicts in the decisions of the FDA where the FDA pediatric advisory committee recommended that the ADHD drugs should not carry the serious black box warnings on them and must have labels on them that will make the people aware of the fact of the side effects that this medicine can cause to the individuals who are suffering from heart diseases. On the other hand another FDA advisory committee about a month back said that there must be black box warnings that are added on the ADHD drugs because it is fatal for the people who have heart diseases. In the end the FDA advisory just remained focused on the less severe recommendation.

As of a current estimation of the children who are currently suffering from the attention deficit hyperactivity disorder ranges to about 2.5 million in US alone and that is a very high figure, and it includes about 1.5 million adults as well who are suffering from ADHD and who are taking medications to take care of their ADHD symptoms.

ADHD was not recognized much but slowly and gradually it has growing number of cases that are being recognized and reported and that has caused a high surge in the medication so that this condition can be treated and the symptoms of this disorder can be alleviated. There is behavioral therapy that is being given to the individuals who are suffering from the ADHD but the role of medications is big because that is what controls their symptoms.

Another set of serious side effects that are being labeled for the ADHD medications include the growth suppression of children, high risk for psychosis, bipolar illness as well as aggression.

This warning is going to pose threat to a lot of individuals who are currently taking this medicine because this would caution the doctors to be very careful in prescribing that. Another very important aspect that was being brought into consideration was that the doctors should be more vigilant in taking the history because through history it can be better probed whether the individual is suffering from any heart diseases because if they are suffering from heart disease and suffering from ADHD as well then the prescription of ADHD medications must be stopped depending on the severity of the heart conditions. Even if the drug is being prescribed in the presence of the heart condition that is not that severe then a very close observation should be in place to see as to what are the side effects that the individual is going through after the use of the ADHD drugs.

In the end, I would like to say that there should be research done to find more safer drugs for ADHD so that the fears at the ends of both physicians who prescribe them as well as the parents and the children is avoided so that they feel much safe using the ADHD medications, which is really important since there is a huge number of people who are suffering from this illness.

Tags:  

According to a research that was conducted by a group of scientists, it was found that a toxin can open a new avenue in treating the different brain illnesses and conditions. The researchers found that a toxin that was derived from the sea snail attaches itself with the nicotine receptors in the brain and that has shown promising effects to treat the different brain conditions.

It was in 1979 that a scientist discovered that another medical toxin known as conotixin, which is also known as Prialt was the one that got approved in about 2004 and it is this toxin that was being used to treat the cancer pain, pain associated with the injury, failed back surgery, as well as nervous system dysfunction. The new toxin that is being found is known as alpha cotoxin OmIA. This toxin is being taken from the snail known as conus omaria and that is being derived from the cone of the snail. This snail is being found from the Pacific and the Indian oceans.

The researchers are thinking that they will be able to treat the different medical conditions related to brain and those problems include the Alzheimer’s disease, depression, nicotine addiction, as well as even schizophrenia. The researchers added that they will be working on the different diseases separately and will be coming up with the treatment of the different conditions through this toxin. They said that they have to go through the different research layouts to see as to how this toxin will be able to help the different brain diseases. They said that with this toxin they are looking forward to even help people quit smoking. Wouldn’t that be amazing.

The way that this toxin works, which is the OmIA conotoxin is that it binds up with the nicotinic acetylcholine receptors, which is found on the nerve cells that are present in the brain as well as the spinal cord. The nicotinic receptors are those where the nicotine binds up with that is being smoked by an individual. This binding of the nicotine to the nicotine receptors causes the secretion of the neurotransmitters from the nerve cells and that causes an excitatory feeling by these neurotransmitters.

It is also of importance to know that there are different types of nicotinic receptors. These nicotinic receptors are alpha and beta and they both have subcategories in which the alpha has subcategories ranging from 2 till 10 and the beta receptors have categories ranging from 1-4. All these subcategories are known to perform their different functions. All the different subcategories of the receptors are known to perform their own function and that are different. The researchers were thinking that it would bring about a great influence in treating different conditions by making the different subcategories work really effectively. For example in the Parkinson’s disease the neurotransmitter dopamine decreases in amounts and thus causes a problem known as tremors. If the specific receptors are being made to secrete the neurotransmitter dopamine then this can cause the prevention of tremors in Parkinson’s disease. This then would be a big breakthrough in eradicating the different brain illnesses.

There was another comment that was made to making the smokers aware that if their child in the mother’s womb is being exposed to the smoke, then this can cause the child to have a significant variation in the structure of the nicotinic receptors and the smokers should either quit smoking for that specific period of time or should take measures where they are not smoking in home or are not making their wives smoke passively, which can directly affect the health of their child.

Now coming back on the topic, these toxins that are being found are known to bind directly to the nicotinic receptors. It is being thought that the nicotinic receptors are responsible for alcohol addiction and that with these toxins that bind to these receptors they can cause the individual to not have the craving for alcohol. It is also known that one of the nicotinic receptors are known to be related to the memory and it affects the memory if there is any problem related to these nicotinic receptors and with this toxin it is being thought that the problem of memory related to Alzheimer’s can be treated. Also the people who smoke can be made to leave the cigarettes with the help of this toxin.

Another major breakthrough that can be achieved is that the nicotinic receptors are known to secrete two other neurotransmitters known as serotonin and norepinephrine and the imbalance in these neurotransmitters result in the mood disorders and these can be used to treat the two common disorders known as depression and schizophrenia, which is going to help large number of people throughout the world.

The researchers added that this toxin will not become a drug but will be used as a tool to identify and isolate the different receptors and they will make the medicines according to that. He recommended that the receptors will be the locks whereas the medicine will be the key to open up these receptors. They added that they need to find as to the exact neurotransmitters that are present because the making of the specific drugs will be dependent on the finding of the specific receptors and their shape so a very close model key can be built in the form of a medicine that would unlock it and give the desired results.

Tags:  

Cancer of the bowel is one of the biggest killer of millions of people throughout the world. The reason that this cancer becomes more lethal is the fact that it metastasizes to the different organ systems at a much faster rate. In UK alone this cancer is the cause of about 50 deaths per day from bowel cancer and there are about 18,000 men who fall victim to this cancer and about 16,000 women who fall in this category. This just needs a lot of awareness among people as to what are the different measures that they need to take to prevent the bowel cancer. Since this disease is growing at a very aggressive rate we all need to do a lot more than what we are doing now. There was a very discouraging news that came up in terms of bowel cancer.

Recently the NHS in UK proposed that the two drugs known as Avastin as well as Erbitux should not be prescribed. They said that there was insufficient evidence to support that these two drugs are helping the people who are suffering from the bowel cancer. This proposal has faced a lot of opposition of the different groups and organizations as well as a lot of people who are suffering from the bowel cancer. These people said that they just cannot think that they would have survived without the use of Avastin or Erbitux because for them these medicines are the hope and if these medicines are being taken away from them then they would not be able to live. It is similar to ask a person that he would not be getting oxygen to breathe.

A lot of people have shared that they just could not believe that this kind of proposal has been raised since there are so many evidences where people have got so much benefit from these drugs and that these medicines have been able to give them their life back. The different charitable organizations have said that these drugs are the best known option for the people who are suffering from cancer that has spread to the different organ structures. They are also saying that these drugs are also miracle drugs because they are known to increase the life expectancy of the individuals by four to six months and that is a great deal of time for a person who is to die in a day or two without it. It is really concerning that Scotland has made a similar decision as well.

It is a fact that the bowel cancers can be treated if detected early and they are not treatable if they are being detected in the later stages. The drugs Avastin and Erbitux are monoclonal antibodies and they are just similar to the biological agent such as Herceptin that is being used to treat the breast cancer. The Avastin and the Erbitux are being given to the patients in whom the cancer is being known to metastasize to the liver and the lungs and they bear a potent effect by killing the tumor cells. Avastain is also known as bevacizumab and it kills the cancer cells by simply blocking up the food supply of the tumor cells, which is blood and thus prevents the spread of the tumor from growing into the body.

There are a lot of patients who have come up protesting that this proposal must not be considered because this will just kill thousands of people just because they did not get the treatment for their illness. There are people who said that since they have been taking these medications they are feeling much much better than before and they just do not know as to what is gong to happen to them if the drug is being taken away from the market and is not available to them.

These medicines are being used as a last resort of treatment and is being given when all the other chemotherapies have failed and that is what makes a drug of hope for a lot of people who consider it the last step and a savior that separates their life from death. The drug Erbitux, which is also known as the cetuximab does its work by stopping the proliferation of the cancerous cells. These drugs have also been known to shrink the size of the tumor by about 50% in about four months’ time.

Another reason that is being discussed mostly is the cost of the drugs and that Avastin costs about 16,800 pounds whereas Erbitux costs about 11,700 pounds and that is another reason that the NHS is thinking to stop the prescription of these two drugs saying that they have scarce resources and they do not think that these medicines are having any beneficial effect on the patients at all. On the other hands the doctors who are giving these therapies to their patients are saying that they have found good results in people in whom all other forms of therapies have been useless where these two medications are proving beneficial.

People are saying that this is a very cruel step by the NHS because this can just cause loss of lives of a lot of people and people just will be dying miserably if this drug is being taken off of market or is being stopped being written as a prescription drug. The importance of the treatment through this drug can only be known by a person who is being told that he only has a week to live and that he has a chance to survive for about four to six months if he opts for Avastin and Erbitux and one can easily understand as to how important these drugs are for individuals who are standing at that stage of life and death. People are being saying that they just cannot believe that the NHS is not willing to fund the drugs that are saving the lives of millions of people who are suffering from this horrendous disease.

Tags:  

Acne is a very common problem and a lot of people especially youngsters are suffering from acne problems. Well it is not only the youngsters but also the adults who are victimized by this problem. The most popular drug to treat acne had been Accutane until there have been new findings about this medicine, which state that this drug, Accutane, which is also known as isotretinoin is an anti acne drug, which is connected to cause a rise in the cholesterol levels in a higher percentage of people than was previously thought. This drug also raises the level of fats in the blood, which are triglycerides, as well as elevating the levels of the liver enzymes.

This drug has been known to increase the level of cholesterol in the body through the clinical trials, but since it is causing this problem in a large number of patients is something that is getting the people as well as the physicians really worried as it was known to be the promising drug to treat the acne conditions in a lot of people and a lot of people have found benefit from this drug.

The doctors who had been prescribing this medicine said that they have known for long that the Accutane is a medicine that raise the cholesterol levels in the blood and that they have been very cautious in prescribing this medication to the individuals who have had higher cholesterol levels. The doctors also said that when they prescribe the medication Accutane they are much more careful about the cholesterol levels and just monitor it on a consistent basis. It was also added that the level of the cholesterol goes down when the drug level goes down after it is stopped, so it is a temporary side effect of this medication and is not something that just turns out to be a permanent problem.

The concerning thing for the physicians is that the number of people who would suffer from high cholesterol levels that was suggested in the clinical trials for this drug was low and now it is being found out that the numbers have risen very sharply and a very percentage of people who are taking this medication are having higher cholesterol levels. It was also told in another study that the individuals who were using Accutane that one out of every 10 individuals was showing abnormally high levels of specific liver enzymes and these enzymes only rise in the presence of liver disease, which was concerning.

There was a study conducted on patients who were suffering from acne ranging in the ages of 13 to 50. In this study it was found that the individuals before going through the treatment of Accutane had normal levels of triglyceride, cholesterol and liver enzyme levels, but after taking the Accutane the study showed that the triglyceride levels rose in about 44 percent of the patients, high cholesterol was reported in about 31 percent of the patients and there was a rise in 11 percent of people with liver enzymes. This study also mentioned that about 92 percent participants with the liver enzyme abnormalities returned to normal once the treatment was stopped and about 80 percent of people who were suffering from high triglyceride levels and the 79 percent of people with the high cholesterol levels had a return of normal blood work when they were taken off of Accutane.

On the other hand the researchers mentioned that it is important to state that if there are even temporary elevations of cholesterol and triglycerides, this can lead to the development of the metabolic syndrome, which includes high blood pressure, cholesterol abnormalities, increased blood sugar levels etc. It is almost important to state that these metabolic syndromes ultimately lead to the development of the coronary heart disease that can ultimately lead to death.

There are doctors who are saying that they just cannot out rightly advocate to not prescribe the Accutane because that has been the wonder drug that the Dermatology has seen in years and that this study is something that just makes them cautious. They also added that they think that the benefit of this drug outweighs the risks and that this drug has cured about 89% of the patients thus far.

There is a special registry that is being made for people who are taking Accutane where the Food and Drug Administration has asked the physicians to log all their patients who are taking Accutane and that it is necessary for these patients to come and visit their doctors once a month and get their blood work up to see as to whether they have elevated cholesterol and triglyceride levels and if they are elevated then at what level do they stand at. It was also mentioned that the individuals who are getting the Accutane treatment must be observed very closely for the symptoms of depression, irritability, mood swings, as well as suicidal thoughts, aggression, psychosis etc.

If we look at the package insert of Accutane, it states that there are a quarter of patients who will suffer from the elevated triglyceride levels and about 15 percent from the elevated liver enzymes. It is really important that doctors take care at their part in prescribing this medication and on patients part they should come for regular checks to get the levels of cholesterol assessed at regular intervals.

Tags: